Some of the Late Thoroughworts are stlil blooming as October fades into November. They can hybridize with other members of the genus Eupatorium, but this one appears to be a pure strain—note the smooth leaves, with petioles and without teeth, which set this species apart from either Boneset (Eupatorium perfoliatum) or White Snakeroot (Eupatorium rugosum). It was blooming in late October along a seldom-used railroad siding in Oakmont.
From Gray’s Manual of Botany: Eupatorium serotinum Michx. Stem pulverulent-pubescent, bushy-branched, 1-2 m. high; leaves ovate-lanceolate, tapering to a point, triple-nerved and veiny, coarsely serrate, 0.5-1.5 dm. long; involucre very pubescent. Alluvial ground, Md. to Minn., e. Kan., and south w.